Big-box retail development, one of the primary components of urban sprawl, creates conditions that harbor serious potential for urban blight should those stores become vacant. Retail is a fast-changing business, consumers are fickle and big-box buildings are not very adaptable to other uses.
This article in the
Arizona Republic is quite location-specific, but is illustrative of a more general problem that many U.S. metro areas are facing (or may soon face).